Approach
Segregation Tests
- Sifting segregation: side-to-side mechanism of segregation where the fine particles concentrate under the point of impact in a pile, while the coarse particles roll off the pile and locate at the periphery
- Fluidization segregation: top-to-bottom mechanism of segregation where fine particles in an aerated powder accumulate at the top of a powder bed, while the coarse particles deaerate quickly and settle to the bottom of the powder bed
- Sieve cut potency: powder separated by sieving for assay at each size cut
Sifting and fluidization segregation tendencies can be measured via bench-scale tests. Samples subjected to the segregation tests will be analyzed for particle size distribution by us, and if required, will be returned to your laboratory for analysis (e.g., assay via HPLC, pH, reactivity).
We also have the unique capability to perform sifting and fluidization segregation tests with our material sparing segregation testers. It is common in the pharmaceutical industry to have limited sample quantity for analysis, thus, we have developed the material sparing segregation testers to measure particle segregation mechanisms with sample volumes of 10 ml and 50 ml for fluidization and sifting, respectively.
Results
Segregation Test Results
The segregation test results are presented in a detailed report including:
- Graphical and tabular presentation of the data
- Description of the test methods
- Key conclusions for the material’s segregation behavior(s)
One of our engineers will also review the test results with you and answer questions you may have regarding the segregation report conclusions, and their possible implications.
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